Manufacturing of IMP

Innovative and compliant IMP manufacturing

The Nuvisan manufacturing team has a proven heritage of effective product development. These successes are underpinned by our focus on innovation and on the needs of patients and healthcare professionals. We offer a full range of technologies, such as capsules, liquid and semi-solid solutions, that aims to shorten the time to proof-of-concept while establishing a sound foundation for clinical development and commercialisation.

A scientist wearing a labcoat is weighing raw materials under a laminar flow hood

Capsules and over-encapsulation

Nuvisan can support small volume batches via manual filling of capsules as larger batches using our semi-automatic equipment. We are a flexible and reliable partner for your clinical trial supply.

Capsule manufacturing

Custom capsule production: Expertise in hard-gelatin and HPMC capsules for active pharmaceutical ingredients (APIs)
Dosage flexibility: Precise filling to meet trial requirements

Over-encapsulation

Blinding solutions: Encapsulation of tablets or smaller capsules to mask identity for double-blind studies
Placebo matching: Helping ensure indistinguishability between an active drug and a placebo

Powder in bottles

Nuvisan offers formulation development and manufacturing services for a quick entry into early clinical phases, such as liquid formulation and oral powders for extemporaneous reconstitution to be done at the clinical site before administration to patients. Development of diluent can be performed in-house with supportive stability data to help ensure the best use possible and management during the course of the clinical trial.We also have automatic capsule filling equipment.

Semi-solid formulations

We specialise in the development of non-sterile semi-solid formulations (creams, gels, ointments and others). Our scientists provide tailored formulation strategies, minimizing scale-up risks and helping ensure smooth industrial transfer for commercial production. Manufacturing of semi-solid clinical batches is available up to 50 Kg.

Oral liquid formulations

Nuvisan also develops and manufactures oral liquid formulations, including solutions, syrups and suspensions. Those dosage forms allow to initiate quickly the first-in-human studies.

Key capabilities

Custom formulations: tailored solutions to meet therapeutic and patient needs
Scale-up expertise: risk mitigation strategies for seamless production scaling
GMP compliance: adherence to GMP quality standards for clinical and commercial production.
In-house analytical services help ensure robust testing, method validation and regulatory support, making Nuvisan a trusted partner