Our experienced scientists collaborate with your team using advanced functional genomics and in vitro/in vivo assay platforms. This enables us to identify, validate and deconvolute disease-relevant targets, providing a strong foundation for your drug discovery and development.
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Cell-based assays are crucial for drug discovery and development, providing a realistic biological context. Our biology team offers disease-relevant in vitro and in vivo models to identify leads and targets, including high-throughput formats using specialised chemical libraries. Additionally, these models help determine the structure-activity relationships of drug candidates, validate signaling pathways and mechanisms of action and identify biomarker candidates to support the success of the project.
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Assessing efficacy and pharmacokinetics in living organisms, in vivo pharmacology helps provide insights into drug interactions, metabolism and excretion, while identifying potential biomarkers and side effects. We offer disease-relevant models for various indications and provide in vivo biodistribution studies for lipid nanoparticles and adeno-associated viruses.
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