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Design and synthesis 

Helping transform hits into medicines

We are chemists with extensive expertise in all aspects of drug discovery. By collaborating with colleagues in digital life sciences, screening, DMPK and other key research functions, we simplify the complex process of transforming initial hit chemistries into effective medicines. Our team utilises cutting-edge tools and innovative problem-solving techniques to advance drug development, helping ensure the best outcomes for your projects.

Scientist running a reaction under an inert atmosphere

Comprehensive chemistry solutions for drug discovery 

Design and synthesis are central to successful hit-to-lead campaigns. Our team of over 100 PhD-level chemists and experienced lab professionals, with backgrounds from big pharma, biotech and top universities, excels in small-molecule medicinal chemistry. We offer hands-on experience across all stages of drug discovery, including high-throughput screening and compound optimisation. With expertise in computational chemistry and integrated data science, our team ensures effective use of modelling and computer-aided approaches. Additionally, we provide synthetic chemistry services for client-designed compounds, route scouting and radiolabelled compound production. 

Our services include:

 
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