• contact us navContact Us
  • search navSearch
Let's connect

Want to discuss your project or have any questions?

Biophysics

Enhancing drug discovery with advanced biophysical insights

Biophysical methods are crucial in the early drug discovery process. Our state-of-the-art biophysical platform can accelerate your discovery programs by providing in-depth analysis of compound–target interactions. We offer fragment screening to identify low-affinity binders in primary hit-finding campaigns and use orthogonal methods for hit validation of compounds from biochemical and cellular assays as well as screening campaigns.

Placing samples into the instrument for SPR analysis

Tailored biophysical methods for comprehensive drug discovery support

We work closely with you to determine the most suitable methods for your drug discovery project. Utilising a comprehensive range of biophysical techniques, we identify target engagement and validate hit lists. Furthermore, we offer complete kinetic and thermodynamic characterisation of novel compounds to support hit profiling, structure-activity relationships (SAR) and understanding their mode-of-action (MoA). Our biophysics team collaborates seamlessly with our protein sciences, screening, biochemistry and structural biology teams to ensure a holistic approach. Our experienced biophysicists provide access to a state-of-the-art biophysics toolbox, which includes:

Related topics & resources

Scientists in the lab carry out protein analysis experiment

Protein sciences

Discover how we can help drive your project with our protein production and purification solutions.

learn more
Evaluation of MS performance

Mass spectrometry

Explore our mass spectrometry services supporting your drug discovery efforts.  

learn more
Discussing new lead optimization strategies identified from a new target-compound structure.

Structural biology

Our range of structural biology solutions support you in your hit and lead optimisation endeavours.

learn more
 
v.1.1.1203